Chemical biology is a scientific discipline spanning the fields of chemistry, biology, bioinformatics and statistics. In this field, our network (GDR Chembioscreen) specifically aims at providing tools for the use of chemical probes to the study and manipulation of biological systems. Such probes are mostly selected from chemical libraries through screening methodologies, either on cells or complex systems to search for a desired phenotype (the so-called forward chemical genetics, or phenotypic screening) or on a defined target (reverse chemical genetics). These approaches have been accelerated with the development of high throughput screening platforms in academia and the access to large collection of chemicals issued from synthetic chemistry or from natural extracts.
"ChemBioScreen" : a network of French researchers involved in chemical biology approaches
With an experience of more than 10 years, numerous investigators involved in the field of chemical biology and academic screening platforms have joined together to provide a new framework for the rising of chemical biology as a field per se in France.
This led to the creation of the GDR "ChemBioScreen", a CNRS initiative.